The Best Kratom Potentiators To Use in 2020

An introduction to Kratom Potentiators

At some point in your kratom journey, you may start wondering how you can make the herb’s effects even more intense. You may want to do this in a bid to reduce the amount of cash you are spending on kratom i.e., get the same effects while using a smaller dose, or you simply want to get a bigger hit out of your current dose.

So, is it possible to enhance the effects of kratom without upping your dosage? Yes, it is, by using kratom potentiators.

This article will let you in on what potentiators are, as well as the different types of kratom potentiators that you can use. Read on.

kratom potentiators

What are Kratom Potentiators?

Simply put, a potentiator is a substance that enhances the effects of another compound. A good example of potentiators is medications. Why do you think you are advised against using different types of medicines together? It is because they can enhance each other’s effects, thereby predisposing you to the side effects that come with overdosing on a drug.

Kratom potentiators, therefore, are substances that enhance the effects of kratom. They can either pronounce those effects, make them set in much faster, make them last longer, or do all of the above.

Nevertheless, there’s a bunch of misinformation regarding the substances that can actually potentiate kratom. Most of them do not, and this is why we have compiled this guide; here, we have a list of substances that have been proven to potentiate kratom.

Best Kratom Potentiators

The following substances can help enhance kratom’s effects:

  • Grapefruit Juice

Grapefruit juice is among the most popular potentiators of kratom in the game. Research shows that the grapefruit has an enzyme that enhances the rate at which the body absorbs alkaloids (the chemical compounds responsible for kratom’s effects).

Additionally, using kratom with grapefruit juice also results in longer-lasting effects. In addition to being a great potentiator, grapefruit is also quite complementary to kratom tea in that it gives the tea a great taste, thereby enhancing your overall kratom experience.

However, what really separates grapefruit juice from other potentiators is that it contains a boatload of vitamin C. Vitamin C is especially beneficial to your immune system, which means that you will be less susceptible to illnesses if you consume it regularly.

  • Chamomile

Chamomile is one of the most readily available substances on the planet. It does not hurt that it is a great potentiator as well. Some of the chamomile’s uses include relieving pain and treating digestive problems. Some people even use it as a remedy for arthritis, burns, gout, and skin disorders. Research shows that chamomile is anti-oxidant, as well as an anti-inflammatory agent.

When you use it alongside kratom, it works to enhance the pain-relieving properties of kratom, thereby making them more powerful as well as long-lasting. This is because chamomile is also a known analgesic and sedative.

To potentiate kratom with chamomile, simply make chamomile tea then add kratom to the solution. Take one chamomile bag and place it in boiling water, then add your dose of kratom and let them boil for about 20 minutes. If the tea is bitter to taste, consider adding some honey to the mix.


  • Black Pepper

Black pepper is one of those substances that can potentiate almost anything due to its ability to increase the absorption rate of compounds. It is no surprise, therefore, that black pepper is an essential ingredient in almost every other health supplement.

So, how is black pepper capable of all this?

One of the compounds in black pepper is piperine. This is a substance that increases the bioavailability of nutrients in the body, as well as inhibiting the premature metabolism of active components.

When looking to potentiate kratom with black pepper, take a pinch of black pepper and add it to a mug of kratom tea. You may even add other potentiators to the mix as well for an even greater effect.

However, since piperine increases the bioavailability of almost any substance, it can be dangerous to use black pepper if you are currently on medications. If this is the case, consider using another potentiator.

  • Turmeric

Turmeric is another excellent potentiator thanks to it being an MAO inhibitor, which means that it works to inhibit the breakdown of essential neurotransmitters in the brain, such as dopamine.

As a result, turmeric can prolong the euphoric effects that come with using kratom, which is a plus if you are using kratom for that effect. For best results, however, you should use turmeric with a kratom strain that has excellent euphoric properties, such as white vein kratom.

Another benefit of potentiating with kratom is that it lengthens the shelf life of kratom powder. As such, you can mix both substances together and store them in a container. Ensure to seal that container.

However, note that turmeric is infamous for triggering adverse side effects when taken with anti-depressants. Additionally, it should not be used with anticoagulants, as it thins the blood.

  • Cayenne Pepper

Cayenne pepper, as a potentiator, works to boost the strength of kratom. To derive its benefits, mix it with kratom tea. Most people, however, just combine it with kratom powder then ingest the mixture directly. Cayenne pepper is quite spicy and, therefore, might be a little too much for some people.

Nonetheless, some people prefer cayenne’s spicy taste to kratom’s bitter one.

  • Watercress

For those that are after kratom’s stimulating effects, this is another excellent potentiator to use. This is because watercress contains minerals that form bonds with kratom’s most powerful alkaloid, mitragynine.

Watercress’s potentiating ability, however, is not limited to stimulating kratom strains as it can also enhance the sedation and relaxation effects of kratom. It works to lengthen the duration of their effects.

  • Valerian Root

Valerian root is renowned for the numerous health benefits it has to offer, such as alleviating pain and anxiety, as well as curing insomnia. These benefits are eerily similar to those of kratom.

Additionally, research shows that potentiating kratom with valerian root can increase the levels of gamma-aminobutyric acid (GABA) in the brain. An increase in GABA levels usually results in a relaxation of brain activity, which is what you need when looking to alleviate anxiety and insomnia.

  • Cat’s Claw

Cat’s claw is indigenous to South America, where it is a popular herbal medicine. However, when it comes to potentiating ability, Cat’s Claw neither boosts nor lengthens the effects of kratom.

However, it is used as a potentiator since it contains alkaloids that are similar to those of kratom. As such, you get to enjoy the effects of both substances simultaneously.

  • Caffeine

Caffeine can boost some of the effects of kratom while working to inhibit the development of some of kratom’s side effects. Caffeine’s ability as a potentiator is due to the fact that it is a stimulant, thus enhancing kratom’s stimulation properties to boost energy levels as well as increasing focus and concentration. It also works to inhibit the lethargic effect that has been known to result from using some strains of kratom.

However, due to caffeine’s immense energizing effects, it would be wise to reduce your kratom dosage, as too much stimulation can be dangerous.

  • Akuamma Seeds

Many kratom enthusiasts regard Akuamma seeds as being some of the best potentiators in the game. This does not come as a surprise, considering that these seeds also contain alkaloids. These alkaloids work to promote a relaxing effect on both the body and the brain.

You can use Akuamma seeds with any type of kratom configuration. However, Akuamma Seeds are just as bitter to taste as kratom powder. Therefore, consider combining both substances in a sweet drink such as yogurt to mask the taste.

Do Kratom Potentiators Raise the Risk of an Overdose?

Since potentiators work to enhance the effects of kratom, can they do so to such a point that your body interprets it as an overdose? This question is especially relevant considering that every kratom expert advises you against exceeding the recommended kratom dose, as you run the risk of experiencing adverse effects.

Simply put, combining two substances that enhance each other’s effects can overwhelm your system. As such, to be on the safe side, only potentiate low doses of kratom. Additionally, avoid over-the-counter potentiators and stick to the natural ones as highlighted above.

Final Thoughts

It is easy to see why one would want to potentiate kratom; if using it by itself feels that nice, how about if one could enhance those effects without increasing their dosage?

Kratom potentiators allow you that benefit. Additionally, potentiating kratom is usually risk-free for the most part. However, before you use any kratom potentiator, make sure that you first take kratom by itself, and you know what to expect. You simply cannot start your kratom journey with a potentiator, as the effects can be too strong for you.

If you are a seasoned user and still experience adverse effects upon potentiating, stop that practice with immediate effect. Also, ensure to keep yourself hydrated whenever you use kratom.